iTIVA Anesthesia3.5 - App Store

TRY IT FOR FREE, 10 USES WITHOUT TIME RESTRICTIONS!

iTIVA is a simulation program that provides information about distribution of drugs based on mathematical models, and it simulate the behavior of a TCI pump (up to 3 drugs at time), obtaining infusion rates to reach and maintain a stable target effect site concentration, those schemes can be implemented in volumetric infusion pumps, and be guided with pharmacokinetics models.
So now pharmacokinetics can become an easy topic and understanding what is going on during a infusion of a intravenous drug, too.

Pharmacokinetic models

iTIVA include 11 drugs and 40 pharmacokinetic models, that are updated continuously:

-Remifentanil
Adults: Minto
, Eleveld, Kim
Kids: Rigby-Jones, Eleveld, Ross

-Fentanyl

Adults: Shafer, Scott

Kids: Ginsberg, Encinas (Neonates)

-Sufentanil

Adults: Gepts, Bovill

Kids: Greely

-Alfentanil

Adults: Maitre

-Ketamine
Adults: Domino, Clements-250

 Kids: Herd, Elkomy

-Procaine
Adults: Seifen

-Lidocaine

Adults: Dyck, Schnider

-Propofol

Adults: Schnider, Eleveld, Marsh, Cortinez

 Kids: Peadfusor, Kataria, Eleveld

-Dexmedetomidine

 Adults: Hannivoort, Dyck, Lin, Venn

Kids: Potts

-Midazolam

Adults: Albrecht, Greenblatt

-Tranexamic

Adults: Grassin-Delyle
Kids: Goobie, Grassun-Delyle

iTIVA also calculate the end tidal (Et) for Isoflurane, Sevoflurane and Desflurane for the MAC age, with the use of the Mapleson equation.

Created by David Ramirez MD, Cali - Colombia. Universidad de Valle. david@itiva.co

. WARNING:

iTIVA is not designed to handle intravenous drugs for individual patients. Its use is limited to educational purposes to demonstrate pharmacokinetic principles when performing intravenous anesthesia. Therefore the user assumes all risks from the use of this application for clinical purposes.
Infusion schemes are obtained from concentrations based on models published in the medical literature; therefore concentrations achieved from these schemes can vary widely, in the same manner for clinical effects.
This application should only be used by people with extensive knowledge in Anesthesiology.

We don't collect any information about you, for more info about our privacy policy, refer to http://itiva.co/privacy.html

Version History - Modify patient data during a running simulation: double tap on anthropometric values
- NEW PROPOFOL MODEL: Eleveld 2 / BJA - 2018
- TCI algorithm improved
- Corrected minor problem with kataria model 3.5 03/14/2019 -Fixed a critical bug in in-App purchase
-iPhone X and iOS 11 support
-Fixed screen compatibility for iPhone 6S, 7S and 8S 3.4.2 12/16/2017 -iOS 11 and Iphone X support
-Minor bugs corrected
-Subscription implemented: Improved App support and frequently App Updates 3.4 12/13/2017 -Improved TCI algorithm: Improved precision, bolus doses are now rounded
-3 new pK models added
-Remifentanil's Eleveld model: A general model for children, adults and obese pts
-Remifentanil's Kim model: for obese pts
-Propofol's Eleveld model, for healthy pts: Better predictability for cases without opioids
-KeO for Dexmedetomidine added for Hannivoort model 3.2.1 09/12/2017 - Improved TCI algorithm
- New pK model for Dexmedetomidine,Haannivoort 2015
- Now you can reach the "effect site" target ultra fast with a loading bolus, just select "Flash" during induction or for target change
- TCI models can be change on the go, in any moment, if you decide that the current model isn't performing how you expected, just tap over the model name in "Target" tab twice
- iTIVA manual completed updated!!
- Minor bugs fixed 3.2 05/08/2017 - Improved TCI algorithm
- Now 3 drugs can be simulated in TCI mode, the third one like an adjuvant
- Lidocaine and tranexamic added
- Fixed some minor issues with the Schnider and Eleveld model for propofol
- Induction time now can be split in two for each drug
- Plasma and effect-site target, can be selected separate for each drug
- In bolus mode, now bolus can be added backward
- Minor bugs corrected 3.01 04/07/2016 - New Pk models for neonates and pediatric patients, for remifentanil, fentanyl, sufentanyl and ketamine
- Propofol Eleveld model was added
- Pk parameters for procaine added
- Pd parameters from one model to other are extrapolated using time to peak method
- For neonates now you can select an age between 0 to 30 days
- Induction time now goes between 2 to 20 min
- In the target tab now if you tap over the model name, you get kinetic constants information
- Fixed some bugs with the notification's sound
- In real-time, the stopwatch now can be set for a given start time (HH.mm:ss)
- In real-time, manual doses now can be added for a specific time (HH:mm:ss)
- Minor bugs corrected 2.4.2 12/05/2015 - Fixed a critical bug during memory restoration 2.4.1 10/02/2015 - Better iOS 9 compatibility
- Fixed english language issue
- TCI algorithm improved
- Minor bugs fixed 2.4 09/22/2015 - Improved TCI algorithm
- Now in TCI mode you can change from a manual dose to TCI
- Procain added
- Minors bugs fixed
- Better compatibility for iOS 8, fixed some minor in App purchases issues 2.3 09/16/2015 -Minor Bug fixes.
-Fix a issue in simulation when target was changed on propofol. 2.2.1 04/18/2014 - The algorithm for calculating perfusions was optimized, now concentrations vary less and perfusions last longer.
- iTiva features a new look, iOS 7 style.
- Data entry was adapted for pediatric patients less than 2 years.
- The meds tab was renewed, with a new list of the most used medications for anesthesia and other useful info.
- Added Restore Mode: Data now is preserved allowing multi-tasking
- Fixed minor bugs 2.2 04/08/2014 -Fix a critical bug that may crashes the program, when someone had the previous version installed. (Conflict with User Defaults)

Version 2.0

-Lots of bugs fixes and performance improvements.
-Added 6 new drugs, before had only remifentanil and propofol.
-Added models for children and more for adults.
-Optimize the algorithm for calculating the doses.
-Improved the pickers in the initial screen, show now information about the models.
- Added Bolus mode for all medicines.
-Improved the timer and give the opportunity to the user to change the time of the timer.
- Fixed notification bugs not showing on the correct time.
- Graph now moves in real time when the timer is activated by showing the concentrations of the drugs.
-Graph now turns in all directions when the iPhone is rotated.
-Added labels to the picker on pump tab showing anthropometric data and drug concentration.
-Fixed multiple bugs on pickers when real time was activated.
-Added a new tab (Meds) with helpful information from various medications.
-Now is possible to extend the simulation time with the application in use.
- Fixed a lot of localizations not all were translated.
-Optimized several objects that weren’t display correctly on iPhone 5.
-Optimized application code, and reducing repeated code improving execution time.
-The application icon changed.
- iPad Support. 2.0.1 02/08/2014 -Lots of bugs fixes and performance improvements.
-Added 6 new drugs, before had only remifentanil and propofol.
-Added models for children, and more for adults
-Optimize the algorithm for calculating the doses.
-Improved the pickers in the initial screen display information about the models.
- Added Bolus mode for all medicines.
-Improved the timer and give the opportunity to the user to change the time of the timer.
- Fixed notification bugs not showing on the correct time.
- Graph now moves in real time when the timer is activated by showing the concentrations of the drugs.
-Graph now turns in all directions when the iPhone/iPad is rotated.
-Added labels to the picker on pump tab showing anthropometric data and drug concrentration.
-Fixed multiple bugs on pickers when real time was activated.
-Added a new tab (Meds) with helpful information from various medications.
-New feature to change App notification sounds.
-Now is possible to extend the simulation time with the application in use.
- Fixed a lot of localizations not all were translated.
- Optimized several objects that weren’t display correctly on iPhone 5.
-Optimized application code, and reducing repeated code improving execution speed .
-The application icon changed.
- iPad Support. 2.0 02/03/2014 - Minor bug fixes 1.02 10/24/2013 1.01 10/15/2013 1.0 04/22/2013